Hi Mike, I use Chrome (well, SRWare Iron, which is Chrome without Google tracking you) to play the game, so it has been developed with Chrome in mind. It does seem that problems of this nature are cropping up lately, since we had this thread too:
http://igpmanager.com/play/?url=forum-thread/2794
The one thing all these problems have in common is they are AJAX requests, being made over a connection created within the page. So they rely on the network being 100% reliable to work. Now that I think of it, I saw someone open a regular page on iGP in a live stream yesterday and it took over 10 seconds to load. If that's happening on these requests they will outright fail.
That would explain why we've got people using Opera, Chrome and IE all experiencing glitches in different areas of the game based on AJAX requests. Perhaps the server is hanging, we'll look in to this.